25-Hydroxyvitamin D (Vitamin D) is an important vitamin for humans of all ages. Though this vitamin exists in some foods, Sunlight and regular exercise are needed to synthesis this vitamin in our body. In Bangladesh, the prevalence of vitamin D deficiency in elderly people and patients with musculoskeletal pain is very high. Furthermore, the association between vitamin D deficiency and COVID-19 outcome has been proved. However, in this pandemic situation, to prevent the spread of coronavirus-19, peoples are advised to stay at home as much as possible that abstains from exposure to Sun and outdoor exercise. To mitigate this problem elderly people and patients with musculoskeletal pain should take vitamin D supplementary in this pandemic period in Bangladesh.