The novel Coronavirus respiratory disease 2019 (COVID-19) has not stopped expanding and impressing the world since it started in Wuhan (China) on December 2019. The first case in Africa was reported in Egypt on February 14th, 2020. Since then, the disease has spread in all African countries and with the high prevalences in the Northern region including Egypt, Algeria, Tunisia and Morocco. The objective of this review is to describe the evolution of this disease in these countries and the measures implemented by their authorities to limit the spread of the virus using available data in the scientific databases (Pub med and Google scholar) and the specialized COVID-19 sites (John Hopkins Institute and our data in the world). We described that the North African countries were and still be affected and efforts are ongoing to control this pandemic disease.